What is a peptide COA?

A Certificate of Analysis is a laboratory document that reports test results for a specific peptide batch, including purity, identity, quantity and other quality parameters.

HPLC purity is the percentage of the sample that matches the target peptide in a high-performance liquid chromatography analysis. Research-grade peptides are usually 95-99%+ pure.

Why is mass spectrometry on a COA important?

Mass spectrometry confirms the identity of the peptide by comparing its measured molecular mass to the theoretical mass of the expected sequence.

Any document can be copied, so buy from suppliers that let you verify the COA against a batch number and that test every batch independently.

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Peptide COA Guide: How to Read a Certificate of Analysis

PEPMAKE Research Team (Laboratory & Content Team)

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📅 2026-08-03

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⏱️ 7 min read

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Peptide COA Guide: How to Read a Certificate of Analysis

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